Bone Bouillon is one of the most efficient recipes in the game in terms of extenuating hunger value from its ingredients. If one Ice is used as a filler, Bone Bouillon will restore almost thirteen times as much Hunger as it's ingredients.
Most sources of Bone Shards are finite, and obtaining more is oftentimes a slow process, or requires players to die. Letting Fish Morsels and Raw Fish spoil, and then hammering the resulting spoiled meat is a safe and reliable, albeit slow source of Bone Shards.
Wilson can create more Bone Shards by combining Hound's Teeth together, assuming he has the Transmute Icky III skill. This can allow for the mass production of Bone Shards, and by extension Bone Bouillon if a reliable source of Hound's Teeth, such as a Hound Mound, is accessible. Note that this either requires a second player, or mass-crafting Bone Shards and then switching character.
Trivia
While no Meats are explicitly required to create Bone Bouillon, it is nonetheless considered to be a Meat food item, likely because of the use of Bone Shards. As such, Wigfrid can eat it, Wurt cannot, and Bunnymen will be hostile to anyone carrying it in their inventory.